Minocycline (Minocin^®, Dynacin^®, Vectrin^®)

  Content:

DOSING

Trade Names:

Minocin* Stiefel Canada Inc.
Dynacin* Medicis
Vectrin* Medicis

Dosage Forms:

• Capsules: Minocycline 50 and 100mg (Minocin* Dynacin*)
• Suspension: Minocycline 50mg (Minocin* Dynacin*)
• Parenteral: Minocycline 100mg (Minocin IV*)

Acne vulgaris

• Minocycline 50-100 mg po bid, tapered to 50 mg/d as acne improves
• Most will show satisfactory improvement with 100mg a day
• Aim should be the prevention of new inflammatory lesions
• Use for 8-12 weeks only if good clinical response
• Avoid long term usage to minimize side effects and to reduce the risk of bacterial resistance (Dermatology 2003; 206(1):37-53)

Rosacea

• Minocycline50-100mg daily until no further new lesions
• Try and maintain control after this by topical therapy alone
• Periodic use such as Minocycline 100mg daily for 1 week per month may be required if topicals alone not sufficient to prevent new lesions

Perioral dermatitis

• Minocycline 50-100mg for 1 month will clear most
• Some may need a further 1-2 months for cure

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