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Rosacea - Patient's guide
Understand Your Options
Understand What To Expect From Treatment:
The major goals of rosacea treatment are to:
- Understand the condition
- Identify and avoid the factors that cause flushing for you and that flare your rosacea
- Control the active symptoms and signs of rosacea
- Achieve optimum maintenance of this condition and its complications
- Understand that this is a chronic condition
Self Help:
1) Aggravating factors - These factors can increase your core body temperature:
- Exposure to weather - sun, cold, wind
- Hot food, hot drinks, and alcohol
- Exercise (you should exercise in cool surroundings and avoid dehydration)
- Medications (you should avoid vasodilating drugs, that is, drugs that expand your blood vessels, and topical steroids)
- Cosmetics (you should avoid greasy, drying, or perfumed products
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2) Daily skin care:
- Avoid hot water, loofahs, and rough towels
- Avoid toners, exfoliating agents, and astringents
- Dandruff – Rosacea frequently coexists with sebhorreic dermatitis or dandruff
3) Cosmetics:
Cosmetic cover-up:
- Anti-redness cream, awaits fuller evaluation - Rosacure® is a silymarin extract that claims to reduce the facial redness in rosacea.
4) Patient Support Groups
Medical Treatment:
- For mild rosacea, topical therapy is always the first choice
- When rosacea is more severe, topical therapy must often be combined with oral treatment
- Creams and oral antibiotics are not effective in treating the flushing of the face, or the broken blood vessels
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Minocycline (Minocin®, Dynacin®, Vectrin®)
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INTRODUCTION
Minocycline inhibits the growth of Propionibacterium acnes. Anti-inflammatory actions.
Drug Class: Antibiotic, Anti-inflammatory-long acting tetracycline...
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CLININCAL EXPERIENCE
Oral antibiotics have had a significant role in the treatment of inflammatory disease such as acne, rosacea, perioral dermatitis and others. Tetracycline has long been the first line antibiotic for acneform eruptions because of its efficacy and affordability although in inconvenience of divides doses on an empty stomach has compromised compliance in some. P. acnes resistance to Tetracycline and Erythromycin has meant looking elsewhere for an alternative antibiotic. Bacterial resistance to Minocycline has been much slower to develop...
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INDICATIONS
Labeled Indications: Dermatologic Dermatologic:
Acne vulgaris,
Inflammatory acne,
Anthrax,
Chancroid,
Granuloma inguinale,
Lymphogranuloma venerum,
Skin and soft tissue infections ,
Syphilis,
Yaws...
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PATIENT PROFILE
Any inflammatory acne or rosacea patient who is not likely to respond to topical therapy alone. If scarring present or nodulocystic acne a more aggressive approach may be necessary...
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DOSING
Capsules: Minocycline 50 and 100mg (Minocin* Dynacin*)
Suspension: Minocycline 50mg (Minocin* Dynacin*)
Parenteral: Minocycline 100mg (Minocin IV*) ...
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EFFICACY
Improvement in inflammatory lesion in acne is about a 20% reduction a month. It may take 1-2 months to see initial benefit. After 6 months there is an approximate 60-70% improvement in inflammatory acne counts. Studies over the last 20 years have shown that tetracycline, erythromycin, doxycycline and minocycline have about the same efficacy in acne...
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COMPLIANCE
All tetracyclines are broad-spectrum bacteriostatic agents. They are well absorbed, although oxytetracycline and tetracycline should not be taken with food. Minocycline as well as Doxycycline are absorbed almost as well on an empty as full stomach...
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SIDE EFFECTS, SAFETY AND RISKS
Discard outdated tetracyclines as degradation products may be toxic.
Not recommended in pregnancy and in children under 8 years of age as permanent enamel hyperplasia, discoloration of teeth, and inhibition of fetal skeletal growth may occur...
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COST OF TREATMENT
Cost of treatment of 1 month of standard dose for acne: Minocycline 100 mg daily for 1 month $42.
Tetracycline 1gm daily for 1 month ...
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View the entire Minocycline (Minocin®, Dynacin®, Vectrin®) presentation.
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